Heparin:Structure, Function, and Clinical Implications
The International Symposium on Heparin, held May 13-15, 1974, in St. Louis, Missouri, as a part of the dedication of the Shoenberg Pavilion of the Jewish Hospital of St. Louis, was conceived as a forum to bring together physicians and scientists with a basic interest in the structure, function and clinical usefulness of heparin. Few naturally occurring substances have commanded the breadth of interest among members of the biomedical research community as this compound has. Aspects of its covalent and three-dimensional structure, its biosynthesis, its interaction with and effect on physiologically important moieties and its use as a therapeutic agent in a variety of disease states have been actively studied for the past several decades. Thus, the present state of these studies seemed to be a timely subject for discussion, not only to gather together in one place representative samples of the myriad of data on heparin but also to underscore the ever increasing necessity for communication between basic research and clinical practice.The content and organization of this monograph reflect the scope and importance of this substance. The first section deals with the molecular properties of heparin, including characterization of the basic structure, its biosynthetic origins, its determination and pharmacological standardization and the role of individual structural elements in its biological properties. The second section deals with the functional consequences of the interaction of heparin with various physiological entities including antithrombin III, platelets, and lipoprotein lipase. The last section deals with the several clinical uses of heparin, emphasizing not only the results of many trials but also the problems that remain to be elucidated.
Beyond its central premise, the book can be read through the connected lenses of Nonfiction. Those themes offer useful points of attention as the characters, ideas, or world develop, especially where the book complicates the expectations of its primary category.
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What the reading experience may hold
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Nonfiction
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Balanced tone · Urgent pace
Best when you want to settle into a longer reading experience.
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Readers who want a thoughtful experience and enjoy noticing the connections beneath a book’s surface story.
This book's DNA
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- ISBN-13
- 978-0-3063-9052-4
- Language
- English
- Edition record
- OL10322745M
A more thoughtful way into this book
This guide uses the edition details and category signals above to help you choose deliberately. It does not replace the author's work or a full review.
Best when you want to settle into a longer reading experience.
Begin with its place in Nonfiction, then notice where the book resists that label.
Read for connection, not completion.
Mark one passage that sharpens the book's central concern and one that complicates it. That tension often reveals more than a quick summary.
Three questions to carry with you
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- How does the book change the way you understand its larger subject?
Editorial framework by Wesley Bryan, BookenDeX Founder and Editor.
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These matches combine shared categories with author, publication-era, and reading-length signals.
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Why it fits: shares Nonfiction, a similar reading length.
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Why it fits: shares Nonfiction, a similar reading length.
